KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK1
All Species:
6.67
Human Site:
T594
Identified Species:
12.22
UniProt:
P57059
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57059
NP_775490.2
783
84902
T594
R
Q
Q
L
R
K
T
T
R
T
K
G
F
L
G
Chimpanzee
Pan troglodytes
XP_531484
783
84972
T594
R
Q
Q
L
R
K
T
T
R
T
K
G
F
L
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544912
898
97147
A718
R
Q
Q
L
R
K
N
A
R
T
K
G
L
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60670
779
85009
A596
R
Q
Q
L
R
K
N
A
R
T
K
G
F
L
G
Rat
Rattus norvegicus
Q9R1U5
776
84890
A596
R
Q
Q
L
R
K
N
A
R
T
K
G
F
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511894
801
88312
A601
R
Q
Q
L
R
K
N
A
R
T
K
G
L
L
G
Chicken
Gallus gallus
Q9IA88
798
88848
A594
R
Q
Q
L
R
K
N
A
R
A
K
G
F
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
V659
E
H
T
Q
Q
Q
H
V
L
Y
Q
Q
E
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
R1051
G
S
L
L
G
T
S
R
V
Y
G
S
Y
R
Y
Honey Bee
Apis mellifera
XP_397175
718
80391
T575
K
I
R
G
D
S
S
T
Q
L
Q
L
L
V
Q
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
P836
I
H
Q
S
P
S
M
P
P
S
Q
M
M
T
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
I372
A
S
P
V
G
H
W
I
P
A
H
V
D
H
Y
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
I493
G
S
P
A
A
S
K
I
S
P
L
V
T
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
69.2
N.A.
81.3
81.6
N.A.
70.4
66.6
N.A.
32
N.A.
28.8
36.5
24.5
N.A.
Protein Similarity:
100
99.6
N.A.
73.6
N.A.
86.2
86.3
N.A.
77
76.6
N.A.
44
N.A.
38
50.9
39.4
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
86.6
86.6
N.A.
80
80
N.A.
0
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
N.A.
80
N.A.
86.6
86.6
N.A.
80
80
N.A.
20
N.A.
20
46.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
27.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
42.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
39
0
16
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% F
% Gly:
16
0
0
8
16
0
0
0
0
0
8
54
0
0
54
% G
% His:
0
16
0
0
0
8
8
0
0
0
8
0
0
8
0
% H
% Ile:
8
8
0
0
0
0
0
16
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
54
8
0
0
0
54
0
0
8
8
% K
% Leu:
0
0
8
62
0
0
0
0
8
8
8
8
24
54
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
16
0
8
0
0
8
16
8
0
0
0
0
0
% P
% Gln:
0
54
62
8
8
8
0
0
8
0
24
8
0
8
16
% Q
% Arg:
54
0
8
0
54
0
0
8
54
0
0
0
0
8
0
% R
% Ser:
0
24
0
8
0
24
16
0
8
8
0
8
0
0
0
% S
% Thr:
0
0
8
0
0
8
16
24
0
47
0
0
8
8
0
% T
% Val:
0
0
0
8
0
0
0
8
8
0
0
16
0
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
0
8
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _